Rapid maxillary expansion in therapy-resistant enuretic children:

To evaluate whether rapid maxillary expansion (RME) could reduce the frequency of nocturnal enuresis (NE) in children and whether a placebo effect could be ruled out. Methods: Thirty-four subjects, 29 boys and five girls with mean age of 10.7 6 1.8 years suffering from primary NE, were recruited. All subjects were nonresponders to the first-line antienuretic treatment and therefore were classified as “therapy resistant.”

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