Surgical evaluation of panoramic radiography and cone beam computed tomography for therapy planning of bisphosphonate-related osteonecrosis of the jaws

Bisphosphonates are one of the first-choice antiresorptive drugs for treating patients with bone disorders characterized by increased bone resorption, such as osteoporosis, hypercalcemia of cancer, multiple myeloma, and bone metastases. Particularly, the formation of osteonecrosis of the jaw is related to longterm treatment with high levels of intravenous bisphosphonates and was first described in 2003.1 This is termed bisphosphonate-related osteonecrosis of the jaw (BRONJ)

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