Parallel Randomized Controlled Clinical Trial in Patients with Temporomandibular Disorders Treated with a CAD/CAM Versus a Conventional Stabilization Splint

Oral appliances (OAs) have been shown in randomized controlled clinical trials (RCTs) to be successful for the treatment of signs and symptoms of temporomandibular disorders (TMD).1–3 However, a systematic review has shown that the quality of TMD RCTs is modest and scarce, and that new and better studies on the topic are needed.4 Although many RCTs have shown that various splint designs (eg, anterior bite, palatal, forward displacement, and prefabricated

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